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Autoimmune Liver Disease Care

For unclear reasons, your body can attack your liver and bile ducts in a trio of diseases known as autoimmune liver disease. Liver specialists in the Sutter Health network are experienced in the diagnosis and treatment of autoimmune liver diseases. If diagnosed and treated early, you can expect a good outcome.

Liver imaging and biopsy

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Featured Services

  • Liver Function Tests
  • Liver Transplant

Managing Autoimmune Liver Disease

What causes the body to attack your liver? Scientists are unclear on the causes and triggers of autoimmune liver disease, which can occur without symptoms or occur with anorexia or fatigue.

Liver specialists at Sutter’s San Francisco Center for Liver Disease are highly experienced in the diagnosis and treatment of autoimmune liver diseases. Our team leads the delivery of care at regional offices throughout Northern California. Here are some of the services we provide. 

Autoimmune Hepatitis Care

In autoimmune hepatitis, the body attacks the cells of the liver, causing inflammation and, over time, cirrhosis and acute liver failure. The disease is more common in women than men and in people who have other autoimmune conditions such as type 1 diabetes and ulcerative colitis. 

Because autoimmune hepatitis can look like other forms of hepatitis on liver function tests, your doctor will run a special blood test to diagnose your autoimmune liver diseases and possibly conduct a liver biopsy. 

Treatment includes anti-inflammatory drugs, which you may need to take for life.

Doctor examining patient abdomen 

Primary Biliary Cirrhosis Care

Primary biliary cirrhosis is a chronic disease that destroys the bile ducts in the liver, causing scarring and cirrhosis. While it frequently occurs without symptoms, it can cause intense itching, fatigue, jaundice and swelling in the abdomen or ankles. 

A liver specialist may recommend a blood test, ultrasound and liver biopsy to diagnose the disease.

Primary Schlerosing Cholangitis Care

Primary schlerosing cholangitis (PSC), a rare chronic disease of the bile ducts, occurs more frequently in men than women and results in scarring and inflammation of the biliary system. It can cause cirrhosis and cancer if untreated, and may require a liver transplant. 

PSC is diagnosed using MRI cholangiopancreatography, an imaging study that can identify the signs of scarring in your bile ducts. If blockages occur in the bile ducts, your doctor may use endoscopic retrograde cholangiopancreatography (ERCP) to clear the blockages. Medication can improve bile flow. You’ll also need regular monitoring through liver function tests.

Clinical Perspectives

Surgeons at work in operating room

Sutter's Leading Liver Transplant Center

Sutter's center for liver transplant, the Barry S. Stein, MD, Department of Transplant at California Pacific Medical Center, has earned national recognition as the only transplant center in the country to achieve better-than-average patient outcomes in both liver and kidney transplant patients.

Nonalcoholic Steatohepatitis (NASH) Research

Sutter Health Nonalcoholic Steatohepatitis (NASH) Research
Hepatology researchers are investigating the cellular and molecular mechanisms underlying hepatitis B, C and other liver diseases. Identifying early molecular or genetic changes - which may be detected before the disease manifests any clinical symptoms - could lead to interventions that reduce the severity of liver disease, or even prevent it from developing. Clinical researchers in the Liver Disease Management and Transplant Program are leading new investigations into hepatitis B and C disease management, hepatoma, hepatitis and HIV co-infection, nonalcoholic steatohepatitis, hepatorenal syndrome, and the care of liver transplant patients.

Sutter Health Nonalcoholic Steatohepatitis (NASH) Research Sutter Health Nonalcoholic Steatohepatitis (NASH) Research

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